王小宁,男,1979年7月出生,博士,药物化学研究所天然药物化学教研室。
电话:0531-88382012
E-mail:wangxiaoning7508@126.com
教育经历:
1997.8-2001.7:山东大学药学院药物化学专业,获理学学士学位
2001.8-2004.7:山东大学药学院药物化学专业,获医学硕士学位
2004.8-2007.7:中国科学院上海药物研究所药物化学专业,获理学博士学位
2007年7月至今,山东大学药学院天然药物化学教研室工作
研究经历:
苔藓植物扁枝藓和小蛇苔化学成分及抗真菌生物活性研究;黄鹌菜中倍半萜及其苷类化学成分和生物活性研究;杜楝、老虎楝和紫椿中柠檬苦素、倍半萜和甾体类化合物的分离、鉴定和细胞毒活性的评价;交让木中结构复杂的生物碱类化合物的分离和结构研究;
讲授课程:
有机化合物波谱解析
天然药物化学
研究方向:
生理活性天然产物研究
发表文章:
1. Wang, X. N.; Yu, W. T.; Lou, H. X. Antifungal constituents from the Chinese moss Homalia trichomanoides. Chemistry and Biodiversity, 2005, 2, 139-145.
2. Wang, X. N.; Fan, C. Q.; Yue, J. M. New pregnane steroids from Turraea pubescens. Steroids, 2006, 71, 720-724.
3. Wang, X. N.; Yin, S.; Fan, C. Q.; Wang, F. D.; Lin, L. P.; Ding, J.; Yue, J. M. Turrapubesins A and B, first examples of halogenated and maleimide-bearing limonoids in nature from Turraea pubescens. Organic Letters, 2006, 8, 3845-3848.
4. Wang, X. N.; Yin, S.; Fan, C. Q.; Lin, L. P.; Ding, J.; Yue, J. M. Eight new limonoids from Turraea pubescens. Tetrahedron, 2007, 63, 8234-8241.
5. Wang, X. N.; Fan, C. Q.; Yin, S.; Lin, L. P.; Ding, J.; Yue, J. M. Cytotoxic terpenoids from Turrara pubescens. Chemistry and Biodiversity, Accepted and in press.
6. Wang, X. N.; Gan, L. S.; Fan, C. Q.; Yin, S.; Yue, J. M. Alkaloids from Daphniphyllum macropodum. Helvetica Chimica Acta, Accepted and in press.
7. Wang, X. N.; Fan, C. Q.; Yin, S.; Gan, L. S.; Lin, L. P.; Ding, J.; Yue, J. M. Limonoids and steroids from Trichilia connaroides (Meliaceae). Phytochemistry, Accepted and in press.
8. Zhang, H.; Wang, X. N.; Lin, L. P.; Ding, J.; Yue, J. M. Indole alkaloids from three species of the Ervatamia Genus: E. officinalis, E. divaricata, and E. divaricata Gouyahua. Journal of Natural Products, 2007, 70, 54-59.
9. Yin, S.; Wang, X. N.; Fan, C. Q.; Lin, L. P.; Ding, J.; Yue, J. M. Limonoids from the seeds of the marine mangrove Xylocarpus granatum. Journal of Natural Products, 2007, 70, 682-685.
10. He, X. F.; Wang, X. N.; Fan, C. Q.; Gan, L. S.; Yin, S.; Yue, J. M. Chemical constituents of Polyalthia nemoralis. Helvetica Chimica Acta, 2007, 90, 783-791.
11. Yin, S.; Wang, X. N.; Fan, C. Q.; Liao, S. G.; Yue, J. M. The first limonoid peroxide in the Meliaceae family: walsuronoid A from Walsura robusta. Organic Letters, 2007, 9, 2353-2356.
12. Fan, C. Q.; Wang, X. N.; Yin, S.; Zhang, C. R.; Wang, F. D.; Yue, J. M. Tabularisins A−D, phragmalin ortho esters with new skeleton isolated from the seeds of Chukrasia tabularis. Trtrahedron, 2007, 63, 6741-6747.
13. Chen, Y. Y.; Wang, X. N.; Fan, C. Q.; Yin, S.; Yue, J. M. Swiemahogins A and B, two novel limonoids from Swietenia mahogany. Tetrahedron Letters, 2007, 48, 7480-7484.
14. Gan, L. S.; Wang, X. N.; Wu, Y.; Yue, J. M. Tetranortriterpenoids from Cipadessa baccifera. Journal of Natural Products, 2007, 70, 1344-1347.
15. Zhang, H.; Odeku, O. A.; Wang, X. N.; Yue, J. M. Phragmalin-type limonoids from the stem bark of Khaya grandifoliola. Phytochemistry, Accepted and in press, doi:10.1016/j.phytochem.2007.06.009.
16. Yin, S.; Fan, C. Q. Wang, X. N.; Yue J. M. Lycodine-type alkaloids from Lycopodium casuarinoides. Helvetica Chimica Acta, 2006, 89, 138-143.
17. Yin, S.; Fan, C. Q.; Wang, X. N.; Lin, L. P.; Ding, J.; Yue, J. M. Xylogranatins A-D: novel tetranortriterpenoids with an unusual 9,10-seco scaffold from marine mangrove Xylocarpus granatum. Organic Letters, 2006, 8, 4935-4938.
18. Zhou, Z. W.; Yin, S.; Wang, X. N.; Fan, C. Q.; Li, H.; Yue, J. M. Two new lignan glycosides from Saussurea laniceps. Helvetica Chimica Acta, 2007, 90, 951-956.
19. Sun, S. J.; Lou, H. X.; Gao, Y. H.; Fan, P. H.; Ma, B.; Ge, W. Y.; Wang, X. N. Liquid chromatography–tandem mass spectrometric method for the analysis of fluconazole and evaluation of the impact of phenolic compounds on the concentration of fluconazole in Candida albicans. Journal of Pharmaceutical and Biomedical Analysis, 2004, 34, 1117-1124.
20. 王小宁, 娄红祥. 苔藓植物化学成分及医药应用, 山东卫生. 2003, 54-55.
21. 王小宁, 娄红祥. 苔藓植物中的酚类化合物. 天然产物研究与开发, 2004, 16, 353-358.
22. 王小宁, 娄红祥. 扁枝藓化学成分研究. 中国药学杂志, 2005, 40, 1131-1133.
23. 王小宁, 娄红祥. 扁枝藓中锯齿石松烷型三萜的NMR化学位移全归属. 波谱学杂志, 2005, 22, 35-41.
24. 王小宁,娄红祥. 苔藓植物生物活性成分研究进展. 中草药, 2005, 36, 303-307.
25. 娄红祥, 王小宁. 苔藓植物化学成分研究. 天然产物化学进展; 于德泉, 吴毓林 主编; 化学工业出版社: 北京, 2005年; pp 251-300.
26. 王小宁, 娄红祥. 藓类植物化学成分, 苔藓植物化学与生物学. 娄红祥 主编; 北京科学技术出版社: 北京, 2006年; pp 108-122.
27. 王小宁, 娄红祥. 苔藓植物中的活性成分, 苔藓植物化学与生物学. 娄红祥 主编; 北京科学技术出版社: 北京, 2006年; pp 212-233.