姓名：姜建国 性别：男 职称：教授
学院：轻工与食品学院 最后学历：博士
主要研究方向：藻类次生代谢工程；中药天然产物化学工程
一、简介
姜建国，教授，博士生导师。中国微生物学会分子微生物学与生物工程专业委员会委员，美国食品学会会员，本校“食品化学与生物技术”团队学术负责人，实验室主任。国际著名期刊Mini Reviews in Medicinal Chemistry 特约编辑。1982-1986，华中师范大学，学士；1986-1989，武汉大学，硕士；1992-1995，中科院水生所（武汉），博士；1995-1997，华南理工大学，博士后。1997至今，华南理工大学食品学院，生物科学与工程学院。
二、研究方向
在食品学院与生物学院招收硕士生，在食品学院招收博士生。主要涉及以下两个方向：
1、藻类与微生物次生代谢工程
该方向适合生物化学与分子生物学方向考生。主要从事藻类类胡萝卜素次生代谢途径的分子克隆、代谢途径的分子构建、代谢调控的分子机理。
2、中药与天然产物化学与工程
该方向适合食品专业和药物化学专业的考生。主要从事药食同源品种资源天然产物化学与活性的生物模型研究。
三、主要业绩
主持过4项国家自然科学基金，1项国家科技支撑子课题（项目联系人），3项广东省基金，3项省科技攻关项目，1项广州市科技攻关重点项目等。5项发明专利，专著一部，发表学术论文100多篇，其中SCI论文近60篇（截止2011年9月）。
在国际上率先开展了杜氏藻类胡萝卜素次生代谢途径的分子克隆与代谢调控研究，在次级代谢关键酶基因的克隆与表达，关键酶基因启动子的克隆与功能验证，启动子盐和光代谢调控元件，杜氏藻类胡萝卜素代谢途径的外源表达与基因工程菌的培育，盐胁迫与GPDH表达的相关性，盐度与GPDH同工酶的分子类型与作用等等方面取得了一系列具有创新意义的研究成果。
围绕中药中的药食同源品种资源及其天然活性产物方面进行了多年研究，在国际著名期刊发表了大量学术论文。近期应Mini Reviews in Medicinal Chemistry邀请，提出了一期专刊的主题：本草组学（herbalomics），担任该专辑的主编，该专刊将于2012年秋季出版，预期将会对中药的国际化起到积极作用。
所带的研究生获得过学校和学院设立的所有奖励，包括教育部学术新人、学校优秀博士论文创新基金、各类企业奖学金、南粤优秀研究生，学校优秀研究生，学校十大学术新星等各类奖励荣誉称号。
四、主要论文
以下为近五年发表的SCI论文，均为通讯作者。
2011年
1.Chen, H., Lao, Y.M., Liu, G.N., Jiang, J.G. Effects of salinities on the gene expression of a (NAD+)- dependent glycerol-3-phosphate dehydrogenase in Dunaliella salina. Science of the Total Environment, 2011, 409 (7): 1291–1297. （IF 3.190）
2.Tang, W.Q., Li, D.C., Lv, Y.X., Jiang, J.G. Concentration and drying of tea polyphenol extracted from green tea using molecular distillation and spray drying. Drying Technology, 2011, 29(5): 584–590. （IF 1.662）
3.Qv, X.Y., Zeng, Z.P., Jiang, J.G. Preparation of lutein microencapsulation by complex coacervation method and its physicochemical properties and stability. Food Hydrocolloids, 2011, 25(6): 1596-1603. （IF 2.659）
4.Ye, Z. W., Liu, G.N., Jiang, J. G. Structural and phylogenetic analysis of a novel ζ-carotene desaturase from Dunaliella bardawil, a β-carotene highly accumulated unicellular alga. Limnology and Oceanography, 2011, 56(1): 133-138. （IF 3.385）
5.Xiao, K.J., Zhong, X.K., Wang, J., Jiang, J.G. Extraction of brown pigment from Rosa laevigata Michx and its antioxidant activity. Pharmaceutical Biology, 2011, 49(7):734-740. （IF 0.638）
6.Chen, H., Jiang, J.G. Toxic effects of chemical pesticides (trichlorfon and dimehypo) on Dunaliella salina. Chemosphere, 2011, 84 (5): 664–670. （IF 3.155）
7.Lao, Y.M., Ye, Z.W., Jiang, J.G., Zhou, S.S. In silico analysis of phytoene synthase and its promoter reveals hints for regulation mechanisms of carotenogenesis in Duanliella bardawil. Bioinformatics, 2011, 27(16): 2201-2208. （IF 4.877）
8.Jiang, M.H., Yang, L., Jiang, J.G. Comparative GCMS analysis of essential oil components extracted by three methods from the flower of Citrus aurantium L. var. amara Engl. Journal of Food Science （in print, IF 1.733）
9.Lu, C.L., Zhu, L., Piao, J.H., Jiang, J.G. Chemical compositions extracted from Wikstroemia indica and their multiple activities. Pharmaceutical Biology, DOI: 10.3109/13880209.2011.596207, （in print, IF 0.638）
10.Lv, W., Piao, J.H., Jiang, J.G. Typical toxic components in Chinese medicine and their toxicology. Expert Opinion on Drug Metabolism & Toxicology, （in revision, IF 3.374）
11.Lu, Q., Li, D.C., Jiang, J.G. Preparation and physicochemical properties of tea polyphenol liposome. Journal of Agricultural and Food Chemistry, （in revision, IF 2.816）
12.Lu, Q., Jiang, J.G. Chemical metabolism of active compounds from natural botanicals. Current Medicinal Chemistry, （in revision, IF 4.630）
2010年
13.Ye, Z. W., Wu, X. M., Jiang, J. G. Knockdown of angiotensinogen by shRNA-mediated RNA interference inhibit human visceral preadipocytes differentiation. International Journal of Obesity, 2010, 34(1): 157-164. （IF 5.125）
14.Jiang, J. G., Zhu, Y. H. Preliminary and Comparative cultivations of D. salina in the photobioreactor with outdoors. Journal of Food Process Engineering, 2010, 33 (1): 104–114. （IF 0.875）
15.Zeng, Z.P., Jiang, J.G. Analysis of the adverse reactions induced by natural product derived drugs. British Journal of Pharmacology. 2010, 159(7) 1374-1391. （IF 4.925）
16.Tang, W.Q., Li, D.C., Lv, Y.X., Jiang, J.G. Extraction and removal of caffeine from green tea by ultrasonic-enhanced supercritical fluid. Journal of Food Science, 2010, 75(4): C363-C368. （IF 1.733）
17.Yang, L., Cao, Y.L., Jiang, J.G., Lin, Q.S., Chen, J., Zhu, L. Response surface optimization of ultrasound-assisted flavonoids extraction from the flower of Citrus aurantium L. var. amara Engl. Journal of Separation Science, 2010, 33(9): 1349-1355. （IF 2.631）
18.Zhong, X.K, Jin, X., Lai, F.Y., Lin, Q.S., Jiang, J.G. Chemical analysis and antioxidant activities in vitro of polysaccharide extracted from Opuntia ficus indica Mill. cultivated in China. Carbohydrate Polymers, 2010, 82(3): 722-727. （IF 3.463）
19.Ye, Z. W., Jiang, J. G. Analysis of an essential carotenogenic enzyme: ζ-carotene desaturase from unicellular alga Dunaliella salina. Journal of Agricultural and Food Chemistry, 2010, 58 (21): 11477–11482. （IF 2.816）
20.Lu, C.L., Li, Y.M., Yang, L., Jiang, J.G., Lin, Q.S, Chen, J., Zhu, L. Extraction optimization of daphnoretin from root bark of Wikstroemia indica (L.) C. A. and its anti-tumor activity tests. Food Chemistry, 2011, 124(4): 1500-1506. （IF 3.458）
21.Jiang, M.H., Zhu, L., Jiang, J.G. Immunoregulatory actions of polysaccharides from Chinese herbal medicine. Expert Opinion On Therapeutic Targets, 2010, 14(12): 1367-1402. （IF 3.649）
22.Li, D.C., Jiang, J.G. Optimization of the microwave-assisted extraction conditions of tea phenols from green tea. International Journal of Food Sciences and Nutrition. 2010, 61(8): 837–845. （IF 0.778）
23.Lu, C.L., Qv, X.Y, Jiang, J.G. Proteomics and syndromes of Chinese medicine. Journal of Cellular and Molecular Medicine. 2010 14(12): 2721–2728. （IF 4.608）
24.Qv, X.Y., Jiang, J.G., Piao, J.H. Pharmacodynamic studies of Chinese medicine at whole animal, cell and molecular levels. Current Medicinal Chemistry, 2010, 17(36), 4521-4537. （IF 4.630）
25.Chen, H., Jiang, J. G. Osmotic adjustment and plant adaptation to environmental changes related to drought and salinity. Environmental Reviews, 2010, 18:309-319. （IF 2.318）
26.Zhao, H.Y., Jiang, J.G. Application of Chromatography Technology in the separation of active components from nature derived drugs. Mini Reviews in Medicinal Chemistry, 2010, 10(13):1223-1234. （IF 2.622）
2009年
27.Zhu, Y. H., Jiang, J. G. Combined toxic effects of typical mutagens – dimethylphenol, tribromethane and dinitroaniline, on unicellular green algae Dunaliella salina. Journal of Food Safety, 2009, 29: 1–13. （IF 0.702）
28.Chen, H., Jiang, J. G. Osmotic responses of Dunaliella to the changes of salinity. Journal of Cellular Physiology, 2009, 219(2): 251 – 258. （IF 3.986）
29.Yang, L., Jiang, J.G., Li, W.F, Chen, J., Wang, D.Y., Zhu, L. Optimum Extraction Process of polyphenols from the bark of Phyllanthus emblica L. based on the response surface methodology. Journal of Separation Science, 2009, 32, 1437 – 1444. （IF 2.631）
30.Liu, G.N., Zhu, Y.H., Jiang, J.G. The metabolomics of carotenoids in engineered cell factory. Applied Microbiology and Biotechnology, 2009, 83(6): 989-999. （IF 3.280）
31.Yan, L., Lao, Y.M., Jiang, J. G. Action Mechanisms of Chinese Herbal Compound at the Molecular Level. Letters in Drug Design & Discovery, 2009, 6(5): 397-402. （IF 0.668）
32.Chen, H., Jiang J. G., Wu, G. H. Effects of salinity changes on the growth of Dunaliella salina and the isozyme activities of glycerol-3-phosphate dehydrogenase. Journal of Agricultural and Food Chemistry, 2009, 57(14), 6178–6182. （IF 2.816）
33.Lao, Y. M., Jiang, J. G., Yan, L. Application of metabonomic techniques in the modernization and toxicology research on Traditional Chinese Medicine. British Journal of Pharmacology, 2009, 157(7):1128–1141. （IF 4.925）
34.Zhong, X.K., Li, D.C., Jiang, J.G. Identification and Quality Control of Chinese Medicine Based on the Fingerprint Techniques. Current Medicinal Chemistry, 2009, 16(23): 3064-3075. （IF 4.630）
35.Ye, Z. W., Wu, X. M., Jiang, J. G. Expression changes of angiotensin II pathways and bioactive mediators during human preadipocytes-visceral differentiation. Metabolism Clinical and Experimental, 2009, 58(9): 1288–1296. （IF 2.538）
36.Li, D.C., Zhong, X.K., Zeng, Z.P., Jiang, J.G., Li, L., Zhao, M.M., Yang, X.Q., Chen, J., Zhang, B.S., Zhao, Q.Z., Xie, M.Y., Xiong, H., Deng, Z.Y., Zhang, X.M., Xu, S.Y., Gao, Y.X. Application of targeted drug delivery system in Chinese medicine. Journal of Controlled Release, 2009, 138(2):103-112. （IF 7.164）
37.Li, Y.M., Zhu, L., Jiang, J. G., Yang, L., Wang, D.Y. Bioactive components and pharmacological action of Wikstroemia indica (L.) C. A. Mey and its clinical application. Current Pharmaceutical Biotechnology, 2009, 10(8): 743-752. （IF 3.455）
38.Yang, L., Jiang, J.G. Bioactive Components and Functional properties of Hottuynia cordata and its applications. Pharmaceutical Biology, 2009, 47(12): 1154-1161. （IF 0.638）
2008年
39.Li, W. F., Jiang, J. G., Chen, J. Chinese medicine and its modernization demands. Archives of Medical Research, 2008, 39(2): 246-251. （IF 1.986）
40.Zhu, Y. H., Jiang, J. G. Toxicity of Carbon Tetrachloride to Dunaliella salina, an Environmentally Tolerant Alga. Journal of Toxicology and Environmental Health - Part A Current Issues, 2008, 71(8) 474 – 477. （IF 1.637
41.Zhu, Y. H., Jiang, J. G., Chen, Q. Influence of daily collection and culture medium recycling on the growth and β-carotene yield of Dunaliella salina. Journal of Agricultural and Food Chemistry, 2008, 56(11): 4027–4031. （IF 2.816）
42.Zhu, Y. H., Jiang, J. G., Chen, Q. Characterization of cDNA of lycopene β-cyclase responsible for high level accumulation of β-carotene in Dunaliella salina. Biochemistry and Cell Biology, 2008, 86(3): 285-292. （IF 2.992）
43.Zhu, Y. H., Jiang, J. G. Continuous cultivation of Dunaliella salina in photobioreactor for the production of β-carotene. European Food Research and Technology, 2008, 227:953–959. （IF 1.585）
44.Ye, Z.W., Jiang J. G., Wu, G. H. Biosynthesis and regulation of carotenoids in Dunaliella: Progresses and Prospects. Biotechnology Advances, 2008, 26(4): 352-360. （IF 7.600）
2007年
45.Jiang, J. G., Wu, S. G., Shen, Y. F. Effects of seasonal succession and water pollution on the protozoan community structure in an eutrophic lake. Chemosphere, 2007, 66: 523–532. （IF 3.155）
46.Jiang, J. G., Shen, Y. F. Development of the microbial communities in Lake Donghu in relation to water quality. Environmental monitoring and assessment, 2007, 127 (1-3): 227-236. （IF 1.436）
47.Jiang, J. G., Huang, X. J., Chen, J., Lin, Q. S. Comparison of the sedative and hypnotic effects of flavonoids, saponins and polysaccharides extracted from Semen Ziziphus jujube. Natural Product Research, 2007, 21(4): 310–320. （IF 0.906）
48.Wang, F., Jiang, J. G., Chen, Q. Progress on molecular breeding and metabolic engineering of biosynthesis pathways of C30, C35, C40, C45, C50 carotenoids. Biotechnology Advances, 2007, 25(3): 211–222. （IF 7.600）
49.Jiang, J. G., Shen, Y. F. Studies on the restoration succession of PFU microbial communities in a pilot-scale microcosm. Chemosphere, 2007, 68: 637–646. （IF 3.155）
50.Zhu, Y. H., Jiang, J. G. cDNA for Phytoene Desaturase in Dunaliella salina and it’s Expressed Protein as Indicators of Phylogenetic Position of the β-carotene Biosynthetic Pathway. Journal of The Science of Food and Agriculture, 2007, 87(9): 1772-1777. （IF 1.360）
51.Chen, Q., Jiang, J. G., Wang, F. Molecular phylogenies and evolution of crt genes in algae. Critical reviews in Biotechnology, 2007, 27(2):77－91. （IF 5.281）
52.Chen, J., Jiang, J. G., Lin, Q. S. Toxicity tests of typical mutagenic phenols on Dunaliella salina. Transactions of the ASABE, 2007, 50(2): 685-688. （IF 0.822）
53.Jiang, J. G., Huang, X. J., Chen, J. Separation and purification of saponins in semen Ziziphus jujuba and their sedative and hypnotic effects. Journal of Pharmacy and Pharmacology, 2007, 59(8): 1175-1180. （IF 1.918）
2003-2006
54.Jiang, J. G. Development of a new biotic index to assess freshwater pollution. Environmental Pollution, 2006, 139: 306-317. （IF 3.395）
55.Jiang, J. G., Xiong, Q. W. An Isozyme Analysis of four species in the Family Cypriniae: Genetic, Taxonomic and Germplasm Significance. Journal of the Science of Food and Agriculture, 2006, 86: 465–472. （IF 1.360）
56.Jiang, J. G., Shen, Y. F. Estimation of the natural purification rate of a eutrophic lake after pollutant removal. Ecological Engineering, 2006, 28: 166–173. （IF 2.203）
57.Yan, Y., Zhu, Y. H., Jiang, J. G. Cloning and Sequence Analysis of the Phytoene Synthase Gene from a Unicellular Chlorophyte, Dunaliella salina. Journal of Agricultural and Food Chemistry, 2005, 53(5): 1466-1469. （IF 2.816）
58.Jiang, J. G., Shen, Y. F. Use of the aquatic protozoa to formulate a community biotic index for an urban water system. Science of the Total Environment, 2005, 346 (1-3): 99-111. （IF 3.190）
59.Zhu, Y. H., Jiang, J. G., Yan, Y., Chen, X. W. Isolation and Characterization of Phytoene Desaturase cDNA Involved in the β-carotene Biosynthetic pathway in Dunaliella salina. Journal of Agricultural and Food Chemistry, 2005, 53 (14): 5593-5597. （IF 2.816）
60.Jiang, J. G., Shen, Y. F. Development of a biotic index using the correlation of protozoan communities with chemical water quality. New Zealand Journal of Marine and Freshwater Research, 2003, 37: 777-792. （IF 0.687）
61.Jiang, J. G., Shen, Y. F. Application and validation of a new biotic index using Date of several water systems. Journal of Environmental Monitoring, 2003, 5(6): 871 – 875. （IF 1.810）