基本信息
姓名: 廖玉才 出生年月: 1954.4
性别: 男 硕/博导： 博导
民族: 汉 开设课程： 分子生物学、遗传学
职称: 教授 研究方向： 1. 麦类作物基因工程; 2.真菌毒素形成与控制分子机理; 3. 植物生物反应器
学位: 自然科学博士
联系方式
办公电话：027-87283008
电子邮件：yucailiao@mail.hzau.edu.cn
个人简介
1983年获华中农业大学作物遗传育种专业硕士学位，1989年荷兰瓦赫宁根大学访问学者，1990-1994年德国亚琛大学分子遗传研究所博士生，1994年获德国亚琛大学分子生物学博士学位；1995-1996年为该所博士后，1997年回国，1998-2002年每年到德国亚琛大学分子生物技术所或英国约翰英纳斯所开展合作科研。主要从事麦类作物抗赤霉病基因工程、镰刀菌毒素形成与控制分子机理、重组抗体分离与表达分析、植物生物反应器等研究，在《Nature Biotechnology》、《Journal of Proteome Research》、《Fungal Genetics and Biology》、《Phytopathology》、《Plant Cell Report》、《Mycological Research》、《遗传学报》等国内外专业期刊发表论文80多篇，已被引用700多次；获省部级一等奖1项、三等奖1项，获授权专利5项，申请专利7项，参编专著教材3部。现为《农业生物技术学报》和《麦类作物学报》编委，《中国农业科技导报》理事，湖北省新世纪高层次人才人选。在读研究生30余人，外籍博士生4人。
科研项目
1. 国家自然科学基金重点项目：基于抗体的植物真菌病害分子控制原理与技术研究
2. 国家自然科学基金面上项目：抗体及其融合分子介导的抗赤霉病基因工程
3. 国家自然科学基金面上项目：我国小麦赤霉病菌的遗传多样性及致病性和产毒性的分子基础
4.“十一”五国家科技支撑计划：食品安全关键技术研究用
5. 农业部948项目：重组抗体及其融合分子介导的植物真菌病害控制技术引进与应用
6. 教育部博士点基金：抗体基因工程及在作物赤霉病抗性改良中的应用
7. 科技部863项目：动植物生物反应器新技术研究
8. 中-俄合作项目：植物抗体的表达及在植物抗病基因工程中的应用
9. 中-德合作项目：抗体融合蛋白防控植物和植物产品中黄曲霉菌及其毒素的研究
10. 农业部重大专项：抗赤霉病转基因小麦新品系和新种质创制
11. 科技部973课题：有害物质从饲料污染到畜禽产品残留的传递规律研究
12. 农业部重点课题：转基因小麦快速甄别及高通量检测技术
发明专利及获奖情况
授权专利：
1. Molecular pathogenicide mediated plant disease resistance. US Patent Number 6825325 B1, Issued on Nov. 30, 2004.
2. Molecular pathogenicide mediated plant disease resistance. Indian Patent Number 192141, Issued on Aug. 17, 2004
3. 镰刀菌毒素的分子检测方法及应用. 专利号：ZL 200410009300.2; 授权日：2007.4.15
4. 一种非抗生素筛选小麦转基因植物的方法. 授权日：2010.10.19
5. 一种农杆菌介导的无抗生素筛选转基因大麦植株的方法. ZL 2007 1 0051390.5; 授权日：2010.5.19
获奖：
1. 小麦抗赤霉病性遗传及体细胞抗病突变体的选育，国家教委科技进步三等奖，1995
2. 食品及食品接触材料有害残留的高通量表征及安全性评价技术，国家质量监督检验检疫总局科技兴检奖一等奖，2010
发表的论文及著作
1. Chen, F.-F., Zhang, J. T., Song, X.-S., Yang, J., Li H.-P., Tang, H., Liao, Y.-C*. Combined metabonomic and reverse transcription PCR analyses reveals systems metabolic changes of Fusarium graminearum induced by Tri5 gene deletion. Journal of Proteome Research, 2011, in press. (﹡通讯作者)
2. Cheng, L., Li, H.-P., Qu, B., Huang, T., Tu, J.-X., Fu, T.-D., Liao, Y.-C*. Chloroplast transformation of rapeseed (Brassica napus) by particle bombardment of cotyledons. Plant Cell Reports, 2010, 29, 37:371-381.
3. Li, X., Zhang, J. B., Song, B., Li, H. P., Xu, H. Q., Qu, B., Dang, F. J., Liao, Y. C*. Resistance to Fusarium head blight and seedling blight in wheat is associated with activation of a cytochrome P450 gene. Phytopathology, 2010, 100:183-191.
4. Xu, Y.-B., Li, H.-P., Zhang, J.-B., Song, B., Chen, F.-F., Duan, X.-J., Xu, H.-Q., Liao, Y.-C*. Disruption of the chitin synthase gene Chs1 from Fusarium asiaticum results in an altered structure of cell walls and reduced virulence. Fungal Genetics and Biology, 2010, 47: 205-215.
5. Li, H.-P., Huang, T., Wang, C.-X., Liao, Y.-C*. An efficient regeneration system of barley cultivars from leaf base segments. Biologia Plantarum, 2009, 53: 733-736.
6. Li, H.-P., Zhang, J.-B., Shi, R.-P., Huang, T., Fischer, R., Liao, Y.-C*. Engineering Fusarium head blight resistance in wheat by expression of a fusion protein containing a Fusarium-specific antibody and an antifungal peptide. Molecular Plant-Microbe Interaction, 2008, 21:1242-1248.
7. Wang, J.-H., Li, H.-P., Qu, B., Zhang, J.-B., Huang, T., Chen, F.-F., Liao, Y.-C*. Development of a generic PCR detection of 3-acetyldeoxynivalenol-, 15-acetyldeoxynivalenol- and nivalenol-chemotypes of Fusarium graminearum clade. International Journal of Molecular Sciences, 2008, 9:2495-2504.
8. Li, H.-P., Zhang, J.-B., Qu, B., Huang, T., Chen, F.-F., Xu, Y.-B., Wu, A.-B., P. Nicholson, Liao, Y.-C*. Phylogenetic species, mycotoxin chemotypes and geographical distribution of Fusarium asiaticum and F. graminearum on wheat spikes throughout China. Journal of Plant Pathology, 2008, 90:3-S3, 89.
9. Hu, Z.-Q., Li, H.-P., Zhang, J.-B., Glinka, E., Liao, Y.-C*. Antibody-mediated prevention of Fusarium mycotoxins in the field. International Journal of Molecular Sciences, 2008, 9: 1915-1926.
10. Qu, B., Li, H.-P., Zhang, J.-B., Xu, Y.-B., Huang, T., Wu, A.B., Zhao, C.-S., Carter, J., Nicholson, P., Liao, Y.-C*. Geographical distribution and genetic diversity of the Fusarium graminearum and F. asiaticum on wheat spikes throughout China. Plant Pathology, 2008, 57: 15-24.
11. Qu, B., Li, H.-P., Zhang, J.-B., Huang, T., Carter, J., Liao, Y.-C*., P. Nicholson. Comparison of genetic diversity and pathogenicity of Fusarium head blight pathogens from China and Europe revealed by SSCP and seedling assays on wheat. Plant Pathology, 2008, 57:642-651.
12. Zhang, J.-B., Li, H.-P., Dang, F.-J., Qu, B., Xu, Y.-B., Zhao, C.-S., Liao, Y.-C*. Determination of the trichothecene mycotoxin chemotypes and associated geographical distribution and phylogenetic species of the Fusarium graminearum clade from China. Mycological Research, 2007, 111:967-975.
13. Liao, Y.-C*., Li, H.-P., Zhao, C.-S., Yao, M.-J., Zhang, J.-B., Liu, J.-L. Plantibodies: A novel strategy to create pathogen-resistant plants. Biotechnology and Genetic Engineering Reviews, 2006, 23:253-271.
14. Li, H.-P., Wu, A.-B., Zhao, C.-S., Scholten, O., Loeffler, H., Liao, Y.-C*. Development of a generic PCR detection of deoxynivalenol- and nivalenol-chemotypes of Fusarium graminearum. FEMS Microbiology Letters, 2005, 243:505-511.
15. Wu, A.-B.，Li., H.-P., Zhao, C.-S., Liao, Y.-C*. Comparative pathogenicity of Fusarium graminearum from China revealed by wheat coleoptile and floret inoculations. Mycopathologia, 2005, 160:75-83.
16. Peschen, D., Li, H.-P., Fischer, R., Kreuzaler, F., Liao, Y.-C*. Fusion proteins comprising a Fusarium-specific antibody linked to anti-fungal peptides protect plants against fungal pathogens. Nature Biotechnology, 2004, 22:732-738.
17. Li, H.-P., Fu, C.-Y., Fischer, R., Liao, Y.-C*. Cloning and characterization of a gene coding for a class I chitin synthase from Fusarium graminearum. Canadian Journal of Plant Pathology, 2003, 25:240-248.
18. Li, H.-P., Fischer, R., Liao, Y.-C*. Molecular evidence for induction of phenylalanine ammonia lyase during Puccinia graminis infection and elicitation in wheat. Canadian Journal of Plant Pathology, 2001, 23:286-291.
19. Zhang, M.-Y., Schillberg, S., Zimmermann, S., Liao, Y.-C., Breuer, G., Fischer, R. GST fusion proteins could cause false positive in screening phage-displayed antibody fragments. Journal of Virological Methods, 2001, 91:139-147.
20. Fischer, R., Liao, Y.-C., Drossard, J. Affinity-purification of a TMV-specific recombinant full-size antibody from a transgenic tobacco suspension culture, Journal of Immunological Methods, 1999, 226:1-10.
21. Fischer, R., Liao, Y.-C., Hoffmann, K., Schillberg, S., Emans, N. Molecular farming of recombinant antibodies in plants. Biological Chemistry, 1999, 380, 7/8:825-839.
22. Spiegel, H., Schillberg, C., Sack, M., Holzem, A., Liao, Y.-C., Fischer, R. Accumulation of antibody fusion proteins in the cytoplasm and ER of plant cells. Plant Science, 1999, 146:1-9.
23. Zimmermann, S., Schillberg, S., Liao, Y.-C., Fischer, R. Intracellular expression of TMV-specific single chain Fv fragments leads to improved virus resistance in Nicotiana tabacum. Molecular Breeding, 1998, 4: 369-379.
24. Vaquero-Martin, C., Liao, Y.-C., Fischer, R. Use of non-radiactive probes to study protein-nucleic acids interactions by U.V.-crosslinking. Biotechniques, 1998, 24: 68-70.