姓名:王成明
性 别:男
籍 贯:安徽舒城
出生年月:1967.12
职 称:教授
最高学历:博士
个人简历:
1989年本科毕业于安徽科技学院畜牧兽医系,1992年硕士毕业于南京农业大学后回安徽科技学院任教。期间于1996.8-1997.6在对外经济贸易大学德语中心集训,1997.8-1998.6作为国家教委代表团的成员访问德国,1998.4-1999.12在安徽科技学院主持畜牧兽医系行政工作。2005.12毕业于美国Auburn大学兽医学院,获生物医学博士学位。2010.5-2012.7任Ross大学兽医学院助理教授,2012.8被聘为“江苏特聘教授”并加盟扬州大学兽医学院,2013.4被聘为美国奥本大学客座教授。
主要从事肺炎衣原体发病机理、分子诊断学、感染和慢性炎症性疾病相关性的研究。迄今已申请/获得13项国际、国内专利,发表论文45篇,在The Journal of Infectious Diseases, Infection and Immunity, Genetics, Genes and Immunity, Journal of Clinical Microbiology 等SCI期刊上发表论文25篇。现为Journal of Microbiology and Microbial Research 的主编, Journal of Infection in Developing Countries 的科学编辑,以及International Journal of Diabetes 和Open Veterinary Journal 的编委。
研究方向和领域:
分子诊断学、兽医微生物学和感染性肥胖(infectobesity)的分子机理。
代表性论著:
1. Zhang J, Wei L, Freeman M, Jaegerson K, Kelly P, Gong J, Xu B, Pan Z, Wang C*. Direct detection of Salmonella spp. in feline and canine feces by a generic and differential FRET-qPCR. PLoS One, 2013.
2. Dutton CS, Revan F, Wang C, Xu C, Norton TM, Steward KM, Kaltenboeck B, and Soto E. Salmonella enterica prevalence in letherback sea turtles (Dermochelys coriacea) in St. Kitts, West Indies. Journal of Zoo and Wildlife Medicine. 2013.
3. Loftis A*, Kelly PJ, Freeman M, Beeler, Wang C. Tick-borne pathogens and disease of dogs in St Kitts, West Indies. Veterinary Parasitology 2013
4. Kelly PJ, Xu C, 2, Lucas H, Loftis A, Abete J, Zeoli F, Stevens A, Jaegersen K, Ackerson K, Gessner A , Kaltenboeck B, Wang C*. Ehrlichiosis, babesiosis, anaplasmosis and hepatozoonosis in dogs from St Kitts, West Indies. PLoS One. 2013;8(1):e53450
5. Wang C*, Kaltenboeck B, and Freeman M (Eds.). Veterinary PCR Diagnostics. Bentham Science Publishers, 2012
6. Wang C, Mount J, Jung E, Butler J, Blagburn BL, and Kaltenboeck B*. Flea feeding patterns in dogs analyzed by real-time PCR of the mammalian hydroxymethylbilane synthase (HMBS) gene. Parasites & Vectors, 5:4, 2012
7. Wu H*, Jaegersen K, Robertson BK, Villafane R and Wang C. Quantitative PCR as a Diagnostic Technique in Veterinary Parasitology. In:Veterinary PCR Diagnostics, Bentham Science Publishers p98-105, 2012
8. Yang L, Zhang LY, Wang C, Wang B, Wang XM, Zeng SM*. Differential expression pattern of ISG15 in different tissue explants and cells induced by various interferons. Microbiology and Immunology 56(3):163-70, 2012
9. Kelly PJ, Stocking R, Xu C, Philips N, Kaltenboeck B, and Wang C*. Identification of feline immunodeficiency virus subtype-B on St. Kitts, West Indies by quantitative PCR. Journal of Infection in Developing Countries, 5 (6), 480-3, 2011
10.Wang C, Kaltenboeck B, and Konrad Sachse*. Chlamydophila. In:Molecular detection of human bacterial pathogens. Edited by Dongyou Liu, CRC Press, Taylor & Francis Group 2011. Pages:523-535. 2011
11.Shaheen BW, Boothe DM*, Oyarzabal OM, Wang C, and Johnson CM. Evaluation of the contribution of gyrA mutation and efflux pumps to fluoroquinolone and multi-drug resistance in pathogenic Escherichia coli isolates from the dogs and cats. American Journal of Veterinary Research 72:25-32, 2011
12.Li, Y, Ahluwalia SK, Borovkovb A, Loskutov A, Wang C, Gao D, Poudel A, Sykes KF, and Kaltenboeck B. Highly efficient Chlamydia pneumoniae vaccine candidates identified from an expression library immunization screen. Vaccine 28:1598-1605, 2010
13.Wang C, Johnson CM, Ahluwalia SK, Chowdhury E, Li Y, Gao D, Poudel A, Rahman KHS, and Kaltenboeck B*. A novel tricolor-fluorescence PCR quantitatively detects and differentiates feline immunodeficiency virus and separates infected from vaccinated cats. Journal of Clinical Microbiology 48:1667-1672, 2010
14.Wang C. Chlamydia pneumoniae Lung Infection in Two Inbred Mouse Strains. LAP Lambert Academic Publishing 2010
15.Wang C*, and Kaltenboeck B. Infectious causes of chronic inflammatory diseases:fact or fiction? World Journal of Diabetes 1:27-35, 2010
16.Wang C, Ahluwalia SK, Li Y, Gao D, Poudel A, Chowdhury E, Boudreaux MK, and Kaltenboeck B*. Frequency and therapy monitoring of canine Babesia spp. infection by high-resolution melting curve quantitative FRET-PCR. Veterinary Parasitology 168:11-18, 2010
17.Shaheen BW, Wang C, Johnson CM, Kaltenboeck B, and Boothe DM*. Detection of fluoroquinolone resistance level in clinical canine and feline Escherichia coli pathogens using rapid and early real-time PCR assay. Veterinary Microbiology 139:379-385, 2009
18.Wang C, Gao D, and Kaltenboeck B*. Acute Chlamydia pneumoniae re-infection accelerates the development of insulin resistance and diabetes in obese C57BL/6 mice. The Journal of Infectious Diseases 200:279-287, 2009
19.Wang C, van Ginkel F, Kim T, Li D, Li Y, Dennis JC, and Kaltenboeck B*. Temporal delay of peak T cell immunity determines Chlamydia pneumoniae pulmonary disease in mice. Infection and Immunity 76:4913-4923, 2008
20.Li Y, Wang C, Allen KE, Little SE, Ahluwalia SK, Gao D, Macintire DK, Blagburn BL, and Kaltenboeck B*. Diagnosis of canine Hepatozoon spp. infection by quantitative PCR. Veterinary Parasitology 157:50-58, 2008
21.Min-Oo G, Lindqvist L, Vaglenov A, Wang C, Fortin P, Li Y, Kaltenboeck B, and Gros F*. Genetic control of susceptibility to pulmonary infection with Chlamydia pneumoniae in the mouse. Genes and Immunity 9:383-388, 2008
22.Wang C, Kim T, Gao D, Vaglenov A, and Kaltenboeck B*. Rapid high-yield mRNA extraction for reverse-transcription PCR. Journal of Biochemical and Biophysical Methods 70:507-509, 2007
23.Wang C*, and Kaltenboeck B. Application of real-time PCR in the molecular microbiology diagnostics. BIOforum Europe 3:37-40, 2007
24.Li D, Borovkov A, Vaglenov A, Wang C, Kim T, Gao D, Sykes KF, and Kaltenboeck B*. Mouse model of respiratory Chlamydia pneumoniae infection for a genomic screen of subunit vaccine candidates. Vaccine 24:2917-2927, 2006
25.Diaz-Perez SV, Ferguson DO, Wang C, Csankovszki G, Wang C, Tsai S, Dutta D, Perez V, Kim S, Eller CD, Salstrom J, Ouyang Y, Teitell MA, Kaltenboeck B, Chess A, Huang S, and Marahrens Y. A deletion at the mouse Xist gene exposes trans-effects that alter the heterochromatin of the inactive X chromosome and the replication time and DNA stability of both X chromosomes. Genetics 174:1115-1133, 2006
26.Wang C*, Norton RA, Macklin KS, and Krehling JT. The effect of chicken anemia and infectious bursal disease vaccines and Marek’s disease on the development of cellulites and myositis lesions in floored-reared MHC-defined broiler chickens. Journal of Applied Animal Research 27:1-5, 2005
27.Wang C*, Macklin KS, Krehling JT, and Norton RA. Influence of infectious bursal disease and chicken anemia vaccines on the development of cellulitis and myositis lesions in cage-reared broilers. Journal of Applied Animal Research 27:65-69, 2005
28.Kaltenboeck B, and Wang C*. Advances in Real Time PCR:Application to clinical laboratory diagnostics. In:Advances in Clinical Chemistry Editor:Greg Makowski. ELSEVIER. 40:219-259, 2005
29.Li D, Vaglenov A, Kim T, Wang C, Gao D, and Kaltenboeck B*. High-yield culture and purification of Chlamydiaceae bacteria. Journal of Microbiological Methods 61:17-24, 2005
30.Wang C, Gao D, Vaglenov A, and Kaltenboeck B*. One-step real-time duplex reverse transcription PCRs simultaneously quantify analyte and housekeeping gene mRNAs. BioTechniques 36:508-519, 2004* denotes the corresponding author
联系方式:
通讯地址:江苏省扬州市扬州大学兽医学院(225009 )
E-mail:wangcm@yzu.edu.cn; chengmingwang@gmail.com
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