姓名：冯红 性别：男
职称：教授 学院：生命科学学院
电子邮件: hfeng@scu.edu.cn, 电话: 028-85412738 (Lab.); 手机: 13980772773
简历
四川农业大学，学士（1985.07）；四川农业大学，硕士(1988.07)；四川大学，博士(2000.07)。
1988.07-1997.09— 四川农业大学，副教授(1996)；
2000.07-2001.12— 成都百奥生物信息科技有限公司，研究发展部经理；
2001.12-2004.08 —美国Clemson University遗传与生物化学系博士后；
2004.12-至今—四川大学生命科学学院任教，教授(2007)。
研究方向
分子微生物学和生物技术相关领域，主要研究方向包括原核功能基因及其转录调控机理，工业酶的生物化学与酶工程以及应用。具体包括:
短小芽孢杆菌（Bacillus pumilus）碱性蛋白酶基因转录调控机理的研究，涉及相关转录因子（hpr,degU/S,SinR等）的克隆、表达、与启动子DNA的互作、基因敲除以及在碱性蛋白酶基因表达等方面的生物学功能。
工业酶（碱性蛋白酶、环氧化物水解酶、角蛋白酶等）的催化特性和分子改造，主要采用3D 结构模型的预测与设计，利用定点突变和分子进化策略改造分析这些工业用酶的催化特性，以期获得更加符合工业应用工艺和技术的突变体酶，同时分析研究结构与功能关系。
在生物技术领域，研究开发农业废弃蛋白质等生物资源的生物转化和利用。
科研项目
自然科学基金项目《短小芽孢杆菌碱性蛋白酶基因的转录调控机理（31171204）》，负责人。
科技部支撑计划课题《甘薯为原料的燃料乙醇生产关键技术研究（2007BAD78B04）》子课题，负责人。
科技部863项目《脱毛碱性蛋白酶基因的分子进化（2006AA02Z221）》，负责人。
论文(*通讯作者)
Wang, Zun; Wang, Hai-Yan; Feng, Hong*. A simple and reproducible method for directed evolution: Combination of random mutation with dITP and DNA fragmentation with endonuclease V. Mol Biotechnol. 2012 (DOI.10.1007/s12033-012-9516-9)
Shao, Huanhuan; Cao, Qinghua; Tao, Xiang; Gu, Tinghong; Chang Mengjie; Huang Chenglin; Zhang, Yizheng; Feng, Hong*. Cloning and characterization of ATP synthase CF1 α gene from sweet potato. Afr J Biotechnol. 2011, 10(82), 19035-19042
Zhang, Lin-Fen; Wu, Jin-Ming; Feng, Hong*. Homology modeling and site-directed mutagenesis studies of the epoxide hydrolase from Phanerochaete chrysosporium. J Biochem. 2011; 149, (6), 673-684 (doi:10.1093 /jb/ mvr015)
Liang,Yuejuan; Zhang, Xiaoyong; Luo, Weijie; Zhong, Zengtao; Lv, Min; Feng, Hong; Zhao, Yun; Huang, Qing. Different multiwalled carbon nanotubes--Enzyme system and enzymatic activity. Prep Biochem Biotech. 2011, 41, (3), 243-251 (DOI: 10.1080/10826068.2011.575315)
Li, Nian; Wu, Jin-Ming; Zhang, Yi-Zheng; Feng, Hong*. Characterization of a unique proline iminopeptidase from white-rot basidiomycetes Phanerochaete chrysosporium. Biochim. 2010, 92, (7):779-788
Zhang, Kun; Feng, Hong*. Fermentation potentials of Zymomonas mobilis and its application in ethanol production from low-cost raw sweet potato. Afr J Biotech. 2010, 9, (37), 6122-6128
张昆,邵欢欢,冯红* 运动发酵单胞菌利用淀粉基质生产乙醇研究进展 （阎文昭 主编）四川省科技出版社, 2010
杨庆军,张小炜,张义正,冯红* 脱毛碱性蛋白酶定点突变的初步分析, 四川大学学报(自然版), 2010, 47, (4)：936-940
杨锦,冯红,万民远，焦惠科，张晓露 张义正，短小芽孢杆菌碱性蛋白酶基因的随机突变，应用环境生物学报, 2010, 16（1）：96-99
He, Ming-Xiong; Li, Yi; Bai, Fan; Liu, Xun; Feng, Hong; Zhang, Yi-Zheng. Ethanol production from raw sweet potato starch by mixed-culture of Paenibacillus sp. and Zymomonas mobilis. Ann Microbiol. 2009, 59, (4):749-754
He, Ming-Xiong; Feng, Hong; Bai, Fan; Li, Yi; Liu, Xun; Zhang, Yi-Zheng. Direct production of ethanol from raw sweet potato starch using genetically engineered Zymomonas mobilis. Afr J Microbiol Res. 2009, 3, (11):721-726
Jiang, Ming-Feng; Li, Xiao; Zhang, Liang; Feng, Hong, Zhang, Yi-Zheng. Gene expression analysis of Phanerochaete chrysosporium during the transition time from primary growth to secondary metabolism. J Microbiol. 2009, 47, (3):308-318
Li, Nian; Zhang, Yi-Zheng; Feng, Hong*. Biochemical characterization and transcriptional analysis of the epoxide hydrolase from white-rot fungus Phanerechaete chrysosporium. Acta Biochim Biophys Sinica 2009, 41, (8):638-647
Wan, Min-Yuan; Wang, Hai-Yan; Zhang, Yi-Zheng; Feng, Hong*. Substrate specificity and thermostability of the dehairing alkaline protease from Bacillus pumilus. Appl. Biochem. Biotechnol. 2009, 159(2):394-403
He, Ming-Xiong; Feng, H., Zhang, Yi-Zheng. Construction of a novel cell-surface display system for heterologous gene expression in Escherichia coli by using an outer membrane protein of Zymomonas mobilis as anchor motif. Biotechnol Lett. 2008, 30:2111-2117
Feng, Hong*. Mutational analysis of bacterial NAD-dependent DNA ligase: roles of motif IV in ligation catalysis. Acta Biochim Biophys Sinica 2007, 39 (8):608-616
Wu, Bo; Hu, Guo-Ku; Feng, Hong; Wu, Jin-Ming; Zhang, Yi-Zheng. Cloning and expression of an alpha-amylase gene from Phanerochaete chrysosporium. Curr Microbiol. 2007, 55(2):105-113
Feng, Hong; Dong, Liang; Cao, Weiguo. Catalytic mechanism of endonuclease V: a catalytic and regulatory two-metal model. Biochem. 2006, 45, (34), 10251-9.
Hu, Guo-Ku; Feng, Hong; Zhang, Tao; Yan, Yong-Hong; Wu, Bo; Jiang, Quan; Wu, Jin-Ming; Zhang, Yi-Zheng; Molecular cloning of cDNAs for 14-3-3 and its protein interactions in a white-rot fungus Phanerochaete chrysosporium. Ann Microbiol. 2006, 56, (3), 191-166.
胡国库; 颜永红; 姜权; 吴波; 冯红; 张义正, 黄孢原毛平革菌酵母双杂交cDNA文库的构建及应用. 应用与环境生物学报 2006, 12, (5), 678-682.
Feng, Hong; Dong, Liang.; Klutz, Athena M.; Aghaebrahim, Nima; Cao, Weiguo, Defining amino acid residues involved in DNA-protein interactions and revelation of 3'-exonuclease activity in endonuclease V. Biochem. 2005, 44, (34), 11486-95.
Feng, Hong; Klutz, Athena M.; Cao, Weiguo. Active site plasticity of endonuclease V from Salmonella typhimurium. Biochem. 2005, 44, (2), 675-83.
黄迎春; 冯红; 孙春昀; 陈永兵, 利用基因芯片检测性传播疾病. 四川大学学报（医学版） 2005, 36, (4), 576-577.
Feng, Hong; Parker, Jeremy M.; Lu, Jing; Cao, Weiguo. Effects of deletion and site-directed mutations on ligation steps of NAD+-dependent DNA ligase: a biochemical analysis of BRCA1 C-terminal domain. Biochem. 2004, 43, (39), 12648-59.
Lu, Jing; Tong, Jie; Feng, Hong; Huang, Jianmin; Afonso, Claudio L.; Rock, Dan L.; Barany, Francis; Cao, Weiguo. Unique ligation properties of eukaryotic NAD+-dependent DNA ligase from Melanoplus sanguinipes entomopoxvirus. Biochim Biophys Acta 2004, 1701, (1-2), 37-48.
黄迎春; 孙春昀; 冯红; 胡晓东; 尹海滨, 利用基因芯片检测转基因作物. 遗传 2003, 25, (3), 307-310.
冯红; 张义正, 炭疽菌不利用硝酸盐突变体的筛选及鉴定. 微生物学通报 2000, 27, (5), 341-345.
冯红; 张义正, 黄孢原毛平革菌木质素过氧化物酶基因对营养的转录应答. 四川大学学报(自然版) 2000, 37(Sup), 153-160.
冯红, 张义正, 木质素过氧化物酶基因5′端上游调控序列的分析. 生物化学与生物物理学报 1999, 31, (6), 669-674.
专利
尹海滨，冯红，杨冬，黄迎春 (2002) 用于转基因植物的监测基因芯片. 专利号: ZL 01 2 14517.3
尹海滨，冯红，杨冬，黄迎春. (2002) 用于动植物及其产品检疫的基因检测芯片,专利号: ZL 01 2 06357.6
尹海滨，冯红，杨冬，黄迎春 (2001) 用于疾病诊断的检测型基因芯片. 专利号: ZL 00 2 44776.2