简历:
薛晓文,博士,中国药科大学药物化学教研室副教授,主要从事有机化学以及药物化学领域的研究。2005年毕业于美国迈阿密大学化学系有机化学专业,获博士学位 (Ph.D.)。2005-2006年美国迈阿密大学化学系博士后。2006年9月回到中国药科大学工作。美国化学会会员。在化学领域的权威杂志美国化学会志(The Journal of American Chemical Society)以及有机化学杂志(The Journal of Organic Chemistry)等上发表了多篇SCI论文。
研究领域:
抗肿瘤药物研究;抗血栓药物研究;药物新合成路线的设计与开发;天然产物合成研究。
主要论著:
1. Lei Yang, Xiaowen Xue,* Yihua Zhang, “Simple and Efficient Synthesis of Belinostat”, Synthetic Communications, in publication.
2. Xueqing Zhao,* Weiping Zhuang, Dongsheng Fang, Xiaowen Xue,* Jingming Zhou, “A Highly Efficient Conversion of Primary or Secondary Alcohols into Their Fluorides with n-Perfluorobutanesulfonyl Fluoride-Tetrabutylammonium Triphenyldifluorosilicate”, Synlett 2009, 779.
3. Benjamin W. Gung,* Xiaowen Xue and Zou Yan, “Enthalpy (H) and Entropy (S) for ∏-Stacking Interactions in Near-Sandwich Configurations: Relative Importance of Electrostatic, Dispersive, and Charge-Transfer Effects”, J. Org. Chem. 2007, 72, 2469.
4. Benjamin W. Gung,* Mehul Patel and Xiaowen Xue, “A Threshold for Charge-Transfer Effects in Aromatic Interactions? Quantitative Study of π-Stacking Interactions ”, J. Org. Chem. 2005, 70, 10532.
5. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “Off Center Oxygen-Arene Interactions in Solution: A Quantitative Study”, J. Org. Chem. 2005, 70, 7232.
6. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “The Strength of Parallel-Displaced Arene-Arene Interactions in Chloroform”, J. Org. Chem. 2005, 70, 3641.
7. Benjamin W. Gung,* Xiaowen Xue, Nina Knatz, and James A. Marshall, “Addition of chiral allenylzinc reagent to acetaldehyde: diastereotopic cyclic transition states with a tetrahedral zinc atom located by ab initio and density functional theory”, Organometallics 2003, 22, 3158.
8. Benjamin W. Gung,* Xiaowen Xue, and William R. Roush, “The origin of diastereofacial control in allyboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen”, J. Am. Chem. Soc. 2002, 124, 10692.
9. Benjamin W. Gung* and Xiaowen Xue, “Asymmetric transition states of allylation reaction: an ab initio molecular orbital study”, Tetrahedron: Asymmetry 2001, 12, 2955.